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Pomc mRNA was suppressed by BPA and E2 in pituitary cultures. Pomc mRNA was suppressed by (a) 10−8 M estradiol and (b) 4.4 × 10−5 M BPA in pituitary explant cultures in both males and females (E2 males, n = 6 to 10; E2 females, n = 10 to 15; BPA males, n = 9 to 15, BPA females, n = 7 to 14). #P ≤ 0.05.
