Table 1.
A Summary of Extragonadal Expression of FSHRs and Putative Actions of FSH
| Species | Extragonadal Tissue/Cell Tissue Type | FSH Action Noted | Reference |
|---|---|---|---|
| Mouse | Bone (osteoclasts) | Bone resorption | Sun et al. (9) |
| Human | Umbilical vein endothelial cells, placenta | Angiogenesis | |
| Human and mouse | Female reproductive tract | Myometrial contractility | Stilley et al. (10, 11) |
| Human | Liver (hepatocytes) | Regulation of LDLR levels | Song et al. (25) |
| Chicken | Adipose | Stimulation of lipid biosynthesis | Cui et al. (35) |
| Human and mouse | Adipose | Beiging and mitochondrial biogenesis, activation of brown adipose tissue and enhances thermogenesis | Liu et al. (14, 36) |