Table 2.

Comparison of patient characteristics based on presence of subclones

		Subclone
		No		Yes		All
Variable	Level	n	%	n	%	n	%	P
ISS	I	44	44.0	87	38.0	131	39.8	.60
	II	33	33.0	82	35.8	115	35.0
	III	23	23.0	60	26.2	83	25.2
Elevated LDH	No	91	86.7	184	78.6	275	81.1	.10
	Yes	14	13.3	50	21.4	64	18.9
Elevated creatinine	No	97	89.8	221	89.8	318	89.8	1.00
	Yes	11	10.2	25	10.2	36	10.2
Anemia	No	95	88.0	227	92.3	322	91.0	.23
	Yes	13	12.0	19	7.7	32	9.0
Hypercalcemia	No	100	92.6	229	93.1	329	92.9	.83
	Yes	8	7.4	17	6.9	25	7.1
Age, y	>60	84	77.8	175	71.1	259	73.2	.24
	18-60	24	22.2	71	28.9	95	26.8
Osteolyses	None	22	21.8	61	25.6	83	24.5	.39
	1	10	9.9	14	5.9	24	7.1
	2	6	5.9	9	3.8	15	4.4
	>2	63	62.4	154	64.7	217	64.0
≥VGPR after induction	No	78	72.2	197	80.1	275	77.7	.13
	Yes	30	27.8	49	19.9	79	22.3
≥VGPR after ASCT	No	57	52.8	145	58.9	202	57.1	.30
	Yes	51	47.2	101	41.1	152	42.9