Table 3.

Results from multivariable Cox regression analysis in patients treated with PAD

	All patients				High-risk patients
	PFS		OS		PFS		OS
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Subclone	1.28 (0.85-1.92)	.233	2.07 (1.15-3.73)	.016	2.11 (1.01-4.43)	.048	3.24 (1.19-8.83)	.022
ISS II	1.20 (0.77-1.88)	.414	1.85 (1.01-3.38)	.046	0.60 (0.26-1.37)	.227	0.93 (0.34-2.55)	.890
ISS III	1.41 (0.86-2.32)	.176	1.63 (0.82-3.26)	.167	0.78 (0.29-2.09)	.625	0.76 (0.23-2.53)	.654
Age	1.01 (0.98-1.03)	.653	1.04 (1.00-1.08)	.034	0.99 (0.94-1.03)	.553	1.00 (0.94-1.06)	.963
High LDH	2.28 (1.38-3.76)	.001	3.29 (1.79-6.06)	.0001	2.19 (0.73-6.55)	.160	4.68 (1.52-14.4)	.007
HR main	1.61 (1.06-2.46)	.025	2.06 (1.23-3.46)	.006	—	—	—	—

Bold type indicates significant P values.