Table 1.

Overview of models used to assess NK cell function in atherosclerosis.

Model	NK cells	Atherosclerosis	Other cells targeted
Anti-asialo GM1 serum10	80% depleted	Reduced	Myeloid cells, epithelial cells, CD8 T cells 60% depleted, NKT cells 60% depleted
Granzyme A-Ly49A transgenic mice6	Depleted	Reduced	Some CD, CD8 T cells, NKT cells
Beige mice3	Function impaired	Reduced	Neutrophils, smooth muscle, macrophages
NcriCre R26lsl-DTA mice1	>90% depleted	Unaffected	ILC1 cells in liver, ILC3 cells in small intestine
Noe mice1 (gain-of-function point mutation in Ncr1)1	Hyperreactive (more IFNγ)	Unaffected	None known, maybe ILC1 and ILC3