Working model of upstream signaling-mediated hypocotyl cell elongation through diverse MAP regulation of cortical microtubules. Arrows show positive regulation, and bar ends show inhibitory action. WDL3 suppresses hypocotyl cell elongation in the light, whereas WDL5 and MDP40 mediate hypocotyl cell elongation in the dark. Ca2+ regulates activity of MDP25 to inhibit hypocotyl cell elongation. In this study, we showed that light and ethylene coordinate MDP60 expression through PIF3, and MDP60 alters cortical microtubule organization via microtubule-destabilizing activity, which promotes hypocotyl cell elongation.