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. 2018 Jan 10;13(1):e0190264. doi: 10.1371/journal.pone.0190264

Table 2. Number of germline and somatic variants identified in three mesothelioma samples using whole genome sequencing.

The percentage of the germline variants identified in this study and reported in European population data from gnomAD are presented in brackets.

SNV Indels
9869 11202 11398 All Patients 9869 11202 11398 All Patients
Germline Identified in both platforms 3,033,980 3,146,317 3,092,543 9,272,840 193,359 190,436 185,905 569,700
(96.8%) (96.8%) (96.8%) (96.8%) (91.7%) (91.8%) (92%) (91.8%)
HiSeq X Ten only 313,015 321,627 407,966 1,042,608 33,143 35,253 41,480 109,876
(42.3%) (42.3%) (41.9%) (42.1%) (58.5%) (58.4%) (59.2%) (58.7%)
BGISEQ-500 only 161,128 118,336 92,050 371,514 7,025 6,931 5,789 19,745
(4%) (2.4%) (4.1%) (3.55%) (13.8%) (13.8%) (11.6%) (13.1%)
Total 3,508,123 3,586,280 3,592,559 10,686,962 233,527 232,620 233,174 699,321
Somatic Identified in both platforms 3,554 2,342 1,955 7,851 197 168 114 479
HiSeq X Ten only 697 424 411 1,532 135 93 78 306
BGISEQ-500 only 540 474 493 1,507 102 156 229 487
Total 4,791 3,240 2,859 10,890 434 417 421 1,272