Table 3. GO based biological processes of 15 highly connected modules in the protein-protein interaction subnetwork of Homo sapiens targeted by phytochemicals of P. longum.
| Cluster-Number | GO-ID | P-value | Description |
|---|---|---|---|
| cluster-1 | 42770 | 1.61E-29 | DNA damage response, signal transduction |
| cluster-2 | 23052 | 7.10E-28 | Signaling |
| cluster-3 | 278 | 9.18E-122 | Mitotic cell cycle |
| cluster-4 | 7186 | 2.09E-122 | G-protein coupled receptor protein signaling pathway |
| cluster-5 | 6325 | 8.92E-63 | Chromatin organization |
| cluster-6 | 7166 | 2.42E-47 | Cell surface receptor linked signaling pathway |
| cluster-7 | 22900 | 2.05E-118 | Electron transport chain |
| cluster-8 | 16055 | 1.77E-27 | Wnt receptor signaling pathway |
| cluster-9 | 19220 | 1.48E-14 | Regulation of phosphate metabolic process |
| cluster-10 | 6357 | 7.67E-21 | Regulation of transcription from RNA polymerase II promoter |
| cluster-11 | 6096 | 8.75E-33 | Glycolysis |
| cluster-12 | 6260 | 2.33E-48 | DNA replication |
| cluster-13 | 9889 | 2.84E-14 | Regulation of biosynthetic process |
| cluster-14 | 3735 | 1.28E-127 | Structural constituent of ribosome |
| cluster-15 | 7049 | 1.44E-41 | Cell cycle |