Table 3.
Efficacy Results After 6 Weeks of Treatment.
| Faster aspart |
Insulin aspart |
ETD, faster aspart – insulin aspart (95% CI) | |||
|---|---|---|---|---|---|
| Baseline | 6 weeks | Baseline | 6 weeks | ||
| HbA1c, % | 7.3 (0.7) | 7.1 (0.7) | 7.7 (0.7) | 7.6 (0.7) | −0.14 (–0.40, 0.11) |
| Fructosamine, μmol/l | 320.5 (42.3) | 318.2 (44.9) | 333.5 (33.4) | 340.8 (28.5) | −11.30 (–26.39, 3.80) |
| FPG, mg/dl | 149.9 (52.6) | 148.8 (55.9) | 167.4 (71.6) | 140.6 (61.8) | 13.5 (–28.2, 55.2) |
| 1,5-anhydroglucitol, μg/ml | 5.2 (3.3) | 5.7 (3.7) | 3.7 (1.9) | 3.6 (2.3) | 0.45 (–0.26, 1.16) |
| 2-h PPG increment, mg/dla | |||||
| All meals | 16.4 (33.9) | 8.5 (30.9) | −3.0 (39.0) | 8.2 (47.2) | −13.94 (–37.05, 9.16) |
| Breakfast | 16.5 (37.4) | 4.3 (48.6) | −10.9 (82.2) | 4.1 (93.5) | −15.46 (–53.4, 22.48) |
| Lunch | 18.2 (67.4) | 11.2 (47.6) | 16.0 (59.0) | 36.2 (53.6) | −23.70 (–59.92, 12.53) |
| Dinner | 14.6 (46.8) | 14.6 (46.8) | −14.0 (59.7) | 4.1 (52.6) | −0.31 (–37.47, 36.85) |
Values are observed mean (SD). CI, confidence interval; ETD, estimated treatment difference; FPG, fasting plasma glucose; PPG, postprandial plasma glucose.
a
2-h PPG increment taken from 7-9-7 self-measured plasma glucose profiles.