Table 2.
Dosimetric Comparison of the Targets Between the ART and Non-ART Plans.a
| Parameters | Non-ART | ART | P Value |
|---|---|---|---|
| PTVnx | |||
| HI | 1.12 (0.03) | 1.11 (0.04) | .076 |
| CI | 0.94 (0.01) | 0.97 (0.02) | .045b |
| Dmax (Gy) | 78.12 (2.55) | 77.15 (1.25) | .034b |
| Dmin(Gy) | 63.42 (1.74) | 64.30 (2.17) | .219 |
| Dmean (Gy) | 72.66 (72.38-73.55) | 73.29 (72.31-73.74) | .335 |
| D95 (Gy) | 70.26 (1.07) | 70.61 (1.17) | .067 |
| D99 (Gy) | 68.24 (1.05) | 68.91 (1.57) | .096 |
| V110 (%) | 0.40 (0.00-1.99) | 0.05 (0.00-0.23) | .033b |
| V100 (%) | 94.77 (2.20) | 96.01 (2.50) | .104 |
| V95 (%) | 99.81 (99.56-100.00) | 99.94 (99.66-100.00) | .011b |
| V93 (%) | 99.99 (99.89-100.00) | 100.00 (99.94-100.00) | .068 |
| PTVnd | |||
| HI | 1.11 (0.01) | 1.09 (0.03) | .796 |
| CI | 0.85 (0.05) | 0.90 (0.01) | .028b |
| Dmax (Gy) | 76.77 (2.29) | 76.71 (1.37) | .877 |
| Dmin (Gy) | 44.31 (8.69) | 47.38 (9.99) | .191 |
| Dmean (Gy) | 71.52 (1.61) | 72.42 (1.57) | .057 |
| D95 (Gy) | 66.33 (2.85) | 68.55 (1.91) | .021b |
| D99 (Gy) | 58.90 (5.74) | 63.43 (2.85) | .031b |
| V110(%) | 0.00 (0.00-0.07) | 0.07 (0.00-0.74) | .807 |
| V100 (%) | 86.25 (5.17) | 91.78 (3.99) | .038b |
| V95 (%) | 95.17 (2.08) | 98.01 (1.78) | .041b |
| V93 (%) | 96.11 (2.32) | 98.48 (1.17) | .038b |
| PTV1 | |||
| HI | 1.28 (0.03) | 1.27 (0.03) | .178 |
| CI | 0.98 (0.05) | 0.99 (0.07) | .019b |
| Dmax (Gy) | 77.50 (1.37) | 77.12 (1.85) | .208 |
| Dmin (Gy) | 51.89 (6.95) | 52.87 (6.15) | .407 |
| Dmean (Gy) | 70.36 (0.71) | 70.66 (1.09) | .285 |
| D95 (Gy) | 63.71 (1.06) | 64.21 (1.10) | .219 |
| D99 (Gy) | 60.16 (2.58) | 61.09 (1.55) | .037b |
| V100 (%) | 98.01 (1.14) | 98.71 (0.97) | .028b |
| V95 (%) | 99.51 (99.07-100.00) | 99.78 (0.59) | .291 |
| V93 (%) | 99.23 (99.51-100.00) | 99.74 (0.24) | .185 |
| PTV2 | |||
| HI | 1.45 (0.07) | 1.44 (0.09) | .418 |
| CI | 0.93 (0.07) | 0.98 (0.01) | .009b |
| Dmax (Gy) | 78.55 (1.84) | 77.90 (1.47) | .531 |
| Dmin (Gy) | 28.17 (25.06-34.17) | 28.44 (26.09-35.91) | .882 |
| Dmean (Gy) | 63.03 (2.55) | 63.10 (1.98) | .207 |
| D95 (Gy) | 53.10 (1.13) | 55.02 (1.07) | .018b |
| D99 (Gy) | 49.11 (1.78) | 50.58 (1.57) | .029b |
| V100 (%) | 95.14 (1.55) | 96.01 (1.17) | .023b |
| V95 (%) | 97.62 (1.29) | 98.07 (1.01) | .030b |
| V93 (%) | 98.01 (0.24) | 99.00 (0.18) | .041b |
Abbreviations: ART, adaptive radiation therapy; CI, conformity index; Dmax, maximum dose; Dmin, minimum dose; Dmean, mean dose; D95, dose to 95% of the volume; D99, dose to 99% of the volume; HI, homogeneity index; V93, percentage of the volume receiving more than 93% of the prescription dose; V95, percentage of the volume receiving more than 95% of the prescription dose; V100, percentage of the volume receiving more than 100% of the prescription dose; V110, percentage of the volume receiving more than 110% of the prescription dose.
aDifference was calculated by paired sample t test or Wilcoxon rank sum test according to data types. Mean (standard deviation) was used for data with normal distribution, whereas median (interquartile range) was used for data with skewed distribution.
bStatistical significance.