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. 2017 Jul 11;16(6):1022–1030. doi: 10.1177/1533034617717863

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — MicroRNA-7 (miR-7) inhibits tumor growth in vivo. A, B, and C, Effect of miR-7 on the growth of SGC7901 cells inoculated into nude mice. Male BALB/cA nude mice were subcutaneously injected with 5 × 10⁶ SGC7901 cells infected with lentiviruses harboring miR-7 negative control (miR-NC) or miR-7. Tumor volume and weight of 6 tumor tissues were monitored over time as indicated, and the tumor was excised and weighed after 14 days. MicroRNA-7 caused a decrease in tumor volume and weight. Bar = 2 mm. D, The expression levels of mTOR proteins from the 3 tumor tissues of miR-7 expressing group were lower than those of the miR-NC group. Data represent mean (standard deviation). *Significant difference at P < .05. **Significant difference at P < .01.