Table 7.

Comparison between classical and composite biomarkers. Classification scores in the one-vs.-all scenario.

Score	Classical biomarkers		Composite biomarkers
	Mean	Std.	Mean	Std.
Cohen's kappa	0.44	0.24	0.54+,†	0.24
gfi AUC	0.83	0.10	0.74−,†	0.24
gsi AUC	0.89	0.10	0.94+,†	0.07
gso AUC	0.77	0.13	0.92+,*	0.08
Averaged AUC	0.83	–	0.87	–

Variation (⁺increase, ⁻decrease) in the classification scores attributable to the composite biomarkers. ANOVA study:

^*significant at the 0.05 probability level,

^†non-significant at the 0.05 probability level.