. Author manuscript; available in PMC: 2018 Mar 6.

Published in final edited form as: Eur J Clin Nutr. 2017 Sep 6;72(1):130–135. doi: 10.1038/ejcn.2017.138

Table 3.

Zinc and multivitamin (MV) treatment Cox regression hazard ratios for risk of anemia outcomes in infants.

	Non-Zinc	Zinc	P	Non-MV	MV	P

Baseline hemoglobin (Hb) ≥ 11.0 g/dL
N	718	669		682	705
Person-months	2168.2	1983.6		2069.4	2082.4
Anemia
No. of cases	598	573		562	609
HR^a (95% CI)	1.0 (N/A)	1.05 (0.93, 1.18)	0.47	1.0 (N/A)	1.09 (0.97, 1.22)	0.14
Adjusted HR (95% CI)	1.0 (N/A)	1.05 (0.93, 1.18)	0.43	1.0 (N/A)	1.09 (0.97, 1.23)	0.14
Anemia + microcytosis
No. of cases	163	137		146	154
HR (95% CI)	1.0 (N/A)	0.91 (0.72, 1.14)	0.41	1.0 (N/A)	1.07 (0.85, 1.34)	0.57
Adjusted HR (95% CI)	1.0 (N/A)	0.91 (0.73, 1.15)	0.43	1.0 (N/A)	1.06 (0.85, 1.33)	0.61
Baseline hemoglobin ≥ 8.5 g/dL
N	971	959		960	970
Person-months	8551.2	8707.2		8581.8	8676.6
Severe anemia
No. of cases	119	118		137	100
HR (95% CI)	1.0 (N/A)	1.00 (0.78, 1.30)	0.97	1.0 (N/A)	0.72 (0.56, 0.94)	0.01
Adjusted HR (95% CI)	1.0 (N/A)	0.99 (0.77, 1.28)	0.95	1.0 (N/A)	0.72 (0.56, 0.94)	0.01
Severe anemia + microcytosis
No. of cases	112	109		127	94
HR (95% CI)	1.0 (N/A)	1.05 (0.80, 1.37)	0.73	1.0 (N/A)	0.74 (0.56, 0.96)	0.02
Adjusted HR (95% CI)	1.0 (N/A)	1.04 (0.80, 1.36)	0.76	1.0 (N/A)	0.74 (0.56, 0.96)	0.03

HR = hazard ratio; MV = multivitamin.