Table 7. Univariate and multivariate Cox proportional hazard analysis of overall survival in GC.
| Variables | n | OS | |||
|---|---|---|---|---|---|
| Univariate | Multivariate | ||||
| HR (95%CI) | p | HR (95%CI) | p | ||
| Age | 0.025 | 0.227 | |||
| <60 | 19 | 1.00 | 1.00 | ||
| ≥60 | 22 | 3.01 (1.15-7.86) | 1.93 (0.66-5.63) | ||
| Sex | 0.796 | 0.526 | |||
| Male | 22 | 1.00 | 1.00 | ||
| Female | 19 | 1.12 (0.47-2.71) | 0.71 (0.25-2.02) | ||
| Histotype | 0.766 | 0.834 | |||
| Intestinal | 23 | 1.00 | 1.00 | ||
| Diffus | 18 | 0.87 (0.36-2.13) | 0.84 (0.16-4.37) | ||
| Differentiation | 0.592 | 1.00 | 0.604 | ||
| Moderate-Well | 20 | 1.00 | 1.00 | ||
| Poor | 21 | 1.27 (0.52-3.10) | 0.75 (0.25-2.21) | ||
| TNM | 0.046 | 0.941 | |||
| I-II | 2 | 1.00 | 1.00 | ||
| III-IV | 26 | 2.65 (1.02-6.95) | 0.94 (0.20-4.36) | ||
| RIP140 | 0.039 | 0.679 | |||
| Low | 22 | 1.00 | 1.00 | ||
| Mod-High | 19 | 2.74 (1.05-7.16) | 0.60 (0.05-6.77) | ||
| LCoR | 0.006 | 0.004 | |||
| Low | 25 | 1.00 | 1.00 | ||
| Mod-High | 16 | 3.84 (1.47-10.02) | 4.94 (1.67-14.6) | ||
Abbreviations: OS, overall survival; HR, hazard ratio; CI, confidence interval; GC, gastric cancer. A backward elimination with threshold of P=0.6 was to select variables in the final models.