Figure 4. Iron influences mitochondrial biogenesis and patient outcome in myeloma.
(A) The expression FPN1 (SLC40A, left panel) and TFRC (right panel) was analyzed in untreated and DFO-treated C2C12 cells determined by GEP. (B) FPN1 expression (SLC40A1, left panel) and TFRC (right panel) was analyzed in untreated and DFO-treated C2C12 cells overexpressing PGC1A. (C) Gene expression of 17 MitoBio genes in untreated and DFO-treated C2C12 cells.