Table 2. Formulation of TMZ-CS nanoparticles using a 23factorial design.
Batches | Factor | Response | % DL | |||
---|---|---|---|---|---|---|
A | B | C | Y1 | Y2 | ||
F1 | -1 | -1 | -1 | 85.93 | 235.54 | 20.12 |
F2 | +1 | -1 | +1 | 78.80 | 334.56 | 19.20 |
F3 | -1 | +1 | -1 | 90.92 | 167.34 | 20.50 |
F4 | +1 | +1 | +1 | 97.85 | 92.50 | 29.50 |
F5 | +1 | +1 | -1 | 92.87 | 110.45 | 26.90 |
F6 | -1 | +1 | +1 | 91.67 | 135.76 | 23.45 |
F7 | -1 | -1 | -1 | 75.32 | 482.50 | 18.75 |
F8 | +1 | -1 | +1 | 93.26 | 98.78 | 25.57 |