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. 2017 Nov 30;8(67):111318–111332. doi: 10.18632/oncotarget.22791

Table 2. Formulation of TMZ-CS nanoparticles using a 23factorial design.

Batches Factor Response % DL
A B C Y1 Y2
F1 -1 -1 -1 85.93 235.54 20.12
F2 +1 -1 +1 78.80 334.56 19.20
F3 -1 +1 -1 90.92 167.34 20.50
F4 +1 +1 +1 97.85 92.50 29.50
F5 +1 +1 -1 92.87 110.45 26.90
F6 -1 +1 +1 91.67 135.76 23.45
F7 -1 -1 -1 75.32 482.50 18.75
F8 +1 -1 +1 93.26 98.78 25.57