Figure 2. Mutational landscape in 6 cHL-derived cell lines and Sanger sequencing validation.

(A) The diagram shows the distribution of mutations per cell line. One SNV is indicated in red, while two SNVs per gene are indicated in dark red. Black boxes correspond to SNVs validated by Sanger sequencing. (B) Representative example, CARD11 mutation in the KMH2 cell line; IGV diagram (Ion Torrent sequencing) and Sanger sequencing representation.