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. 2017 Dec 4;8(67):111697–111714. doi: 10.18632/oncotarget.22902

Figure 4. Evaluation of pro-apoptotic pathway triggered by 6-MITC on Jurkat cells.

Figure 4

Fraction of apoptotic Jurkat cells with active caspase-8 or with altered mitochondrial membrane potential after 24h (A), 48h (B), 72h (C) and representative dot plot of caspase-8 (up) and mitochondrial membrane potential (down) analysis at 72h treatment at 0μM (left) and 8μM (right) (D). Active caspase-8 and altered mitochondrial membrane potential was evaluated by FCM as described in Methods. Each bar represents the mean ± SEM of five independent experiments. Data were analysed using repeated ANOVA followed by Bonferroni post-test. *p<0.05 vs control; **p<0.01 vs control.