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. 2017 Dec 4;8(67):111807–111818. doi: 10.18632/oncotarget.22910

Figure 4. IGF-1 activates the Akt signals and promote sperm motility.

Figure 4

(A) Representative immunoblots showed p-Akt and Akt proteins after IGF-I administration. Actin was used as the control. Relative protein level was shown from 3 independent experiments. (B) Quantification of the ratio of pAkt/Akt from 3 independent experiments. (C-E) Comparisons of semen kinematic parameters including motile (C), progressive and slow sperm (D), VAP, VSL and VCL (E) that were assessed with the computer-assisted sperm analysis (CASA) system. Bars represent mean ± SEM of more than three separate experiments. *P < 0.05, **P < 0.01 and ***P < 0.001.