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. 2017 Dec 5;8(67):111902–111911. doi: 10.18632/oncotarget.22950

Figure 1. The comparison of the four-plasma miRNA signature and the panel of three miRNAs in a development cohort.

Figure 1

A prediction model based on four-plasma miRNA signature (miRs-126, 145, 210, and 205-5p) was developed for distinguishing lung cancer patients from cancer-free smokers. The ROC curve of the four-plasma miRNA signature produced an AUC of 0.96, yielding 91.5% sensitivity and 96.2% specificity. The ROC curve of panel of three miRNAs had an AUC of 0.85, producing 75.5% sensitivity and 85.3% specificity.