Table 5. Association of three significant SNPs with GDM risk.
Gene | Variant | Minor allele | OR (95% CI) | P | OR (95% CI)* | P* |
---|---|---|---|---|---|---|
MTNR1B | rs10830963 | G | 2.1 (1.4 – 3.0) | <0.001 | 2.0 (1.3 – 3.0) | 0.001 |
rs1387153 | T | 1.8 (1.2 – 2.6) | 0.002 | 1.9 (2.3 – 3.9) | 0.001 | |
GCK | rs1799884 | T | 1.9 (1.2 – 3.0) | 0.003 | 2.1 (1.3 – 3.3) | 0.002 |
*Logistic regression analyses adjusted for age and pre-gestational BMI.