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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Am J Surg Pathol. 2018 Feb;42(2):269–276. doi: 10.1097/PAS.0000000000000982

Fig 2. Lymph node biopsy in MYC+ B-ALL/LBL.

Fig 2

A. A core biopsy of retroperitoneal lymph node (H&E, 40×) (case 3) showed diffuse sclerosis with a dense atypical lymphoid infiltrate. B. The infiltrate (H&E, 400×) was composed of intermediate-to-large atypical lymphoid cells with irregular nuclei, fine chromatin, small nucleoli, and variably high nuclear-to-cytoplasmic ratio. Scattered small lymphocytes were intermixed. The tumor cells were positive for PAX5 (C) and showed strong nuclear staining for TDT (D).