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. Author manuscript; available in PMC: 2019 Jan 22.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Dec 27;495(4):2584–2594. doi: 10.1016/j.bbrc.2017.12.125

Figure 1.

Figure 1

AMPK deficiency exacerbates TAC induced heart hypertrophy. (A) The survival rate of WT and AMPK-KD mice after TAC surgery. (B) The representative heart slice. (C) The heart weight divided by the body weight or the left tibia length of WT and AMPK-KD mice under control and 4 weeks TAC conditions. Values are means ± SE, n=5–7 per group, *p<0.05 vs. WT control, #p<0.05 vs. AMPK-KD control, †p<0.05 vs. WT TAC. (D) Immunohistochemistry staining. Hematoxylin and eosin stain (H & E), wheat germ agglutinin (WGA) conjugates staining, Masson Trichrome staining, and immunohistochemical staining with Mac-2 antibody of WT and AMPK-KD mice under control and 4 weeks TAC conditions. Values are means ± SE, n=4–5 per group, *p<0.05 vs. WT control, #p<0.05 vs. AMPK-KD control, †p<0.05 vs. WT TAC.