Cardiac AMPK deficiency exacerbates heart function after 4 weeks of TAC. (A) The representative picture of M-mode echocardiography. (B) The EF, FS, IVSd, LVDs, LVDd, and RWT at basal condition, 2 weeks and 4 weeks after TAC surgery. (C) The quantification of EF, FS, LVDd, and RWT after 4 weeks of TAC surgery. Values are means ± SE, n=4–6 per group, *p<0.05 vs. WT control, #p<0.05 vs. AMPK-KD control, †p<0.05 vs. WT TAC.