. Author manuscript; available in PMC: 2019 Feb 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):e14–e21. doi: 10.1097/QAI.0000000000001573

Table 2.

Surface marker expression on CD4+ and CD8+ T cells from paired blood and adipose tissue (n=10)

	Comparison of median percentage in blood vs. adipose tissue
T cell subset	Median in Blood (IQR)	Median in Adipose Tissue (IQR)	P-value^†
CD4⁺ %^*	42.6 (35.1, 45.8)	33.1 (28.3, 38.9)	<0.01
CD4⁺ PD1⁺% (exhaustion)	24.6 (20.2, 27.0)	24.9 (17.7, 30.5)	0.86
CD4⁺ CD57⁺% (senescence)	2.2 (1.4, 6.6)	5.7 (3.3, 14.9)	<0.01
CD4⁺ CD38⁺% (activation)	4.0 (1.9, 6.3)	2.7 (2.0, 4.2)	0.44
CD4⁺ DR⁺% (activation)	1.0 (0.6, 1.6)	3.5 (1.5, 5.6)	<0.01
CD4⁺ CD69⁺% (activation)	0.3 (0.2, 0.3)	1.3 (0.3, 4.5)	0.02
CD4⁺ CD45RO⁺% (memory)	51.3 (47.6, 62.7)	53.7 (47.6, 69.5)	0.96
CD4⁺ CD45RO⁺ cells expressing CD69 (%)	0.3 (0.3, 0.5)	5.9 (0.3, 6.3)	0.04
CD8⁺ %^*	51.7 (42.7, 59.6)	61.0 (52.8, 67.2)	<0.01
CD8⁺ PD1⁺% (exhaustion)	20.6 (11.4, 27.7)	20.0 (13.4, 25.1)	0.89
CD8⁺ CD57⁺% (senescence)	22.7 (15.2, 26.7)	37.4 (27.6, 45.1)	<0.01
CD8⁺ CD38⁺% (activation)	0.5 (0.5, 0.6)	0.9 (0.5, 1.1)	0.01
CD8⁺ DR⁺% (activation)	0.9 (0.8, 1.2)	5.5 (3.2, 10.3)	<0.01
CD8⁺ CD69⁺% (activation)	0.5 (0.3, 0.8)	1.1 (0.53, 1.4)	0.15
CD8⁺ CD45RO⁺% (memory)	31.3 (18.1, 55.9)	32.6 (20.8, 54.6)	0.31

Represents the percentage of CD3⁺ T cells that expressed CD4 or CD8. All other values represent the percentage of the CD4+ or CD8+ population expressing indicated surface markers.

^†

Wilcoxon Signed Rank Test – a bold p-value indicates the median of differences between paired blood and adipose tissue is not equal to zero with a significance level of 0.05.