Table 3.

Matrix factors for lercanidipine and lercanidipine-d3 (n=6).

QC level	Lercanidipine			Lercanidipine-d3
	Area response		Matrix factor (A/B)	Area response		Matrix factor (A/B)
	A	B		A	B
HQC	452,157	438,987	1.03	227,342	231,982	0.98
MQC-1	225,687	221,262	1.02	231,376	222,476	1.04
MQC-2	67,548	67,468	1.00	229,476	231,794	0.99
LQC	845	820	1.03	221,683	219,488	1.01

A: Mean area response of six replicates prepared by spiking in extracted blank plasma;

B: Mean area response of six replicates prepared by spiking in mobile phase (neat samples).