Fig. 3. Immune cell infiltration into imiquimod (IMQ)-induced psoriatic skin lesions was altered by connective tissue growth factor (CTGF) blocking. The composition of the leukocyte infiltration was analyzed using the markers F4/80 (macrophage), Ly-6G (neutrophil), CD11c (pan-dendritic cell ([DC]), PDCA-1 (plasmacytoid DC [pDC]), CD3 (pan-T cell), and Vγ3 (γδ T cell). The numbers of macrophages, neutrophils, pan-DC, pDC, pan-T cells, Vγ3⁻ T cells (most of αβ T cells), and Vγ3⁺ T cells were counted on three fields per visual field. Values are shown as the mean±standard deviation of the mean (n=4~6). ^*p<0.05 by Mann-Whitney U test (IMQ[+] vs. IMQ[+], anti-CTGF).