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. 2016 Jan 25;6(3):137–149. doi: 10.1016/j.jpha.2016.01.003

Table 1.

Performance characteristics of UV-spectrophotometric methods.

S.No. Diluent λmax (nm) Linear range (µg/mL); molar extinction coefficient, Є (L/mol/cm) LOD (µg/mL) LOQ (µg/mL) Application Reference
1 0.8–2.8 Bulk drug, tablets, creams [9]
2 Methanol 223 1–3.5 0.11 0.33 Tablets [10]
3 Methanol 282 8–24 0.35 0.81 Tablets [11]
4 (a) 0.1 mol/L HCl 222 0.2–4.0; 8.72×104 Bulk drug, tablets SIAM [12]
(b) 0.1 mol/L acetic acid 282 2.0–50; 7.97×103 Bulk drug, tablets SIAM
5 0.1 mol/L HCl 223 1–3.5 0.086 0.26 Tablets [13]
6 Water 283 5–30 0.42 1.3 Bulk drug, tablets, eye drops [14]
7 10–100 mg/mL 1.11 mg/mL 3.36 mg/mL In the presence of degradation products [15]
8 297; 298 5–30 Tablets, creams [16]

SIAM: Stability-indicating assay method.