Table 2. Age-adjusted incidence rates and rate ratios of MCL in Texas and SEER areas, 1995–2013.
| Texas | SEER | |||
|---|---|---|---|---|
| Incidencea (95% CI) | RRb (95% CI) | Incidencea (95% CI) | RRb (95% CI) | |
| Year of diagnosis | ||||
| 1995–1999 | 0.70 (0.63–0.77) | 1.00 (Reference) | 0.80 (0.75–0.85) | 1.00 (Reference) |
| 2000–2004 | 0.91 (0.82–0.99) | 1.26 (1.08–1.46) | 0.94 (0.88–1.00) | 1.14 (1.00–1.30) |
| 2005–2008 | 1.01 (0.93–1.08) | 1.39 (1.21–1.60) | 1.09 (1.03–1.15) | 1.26 (1.11–1.43) |
| 2009–2013 | 1.00 (0.93–1.07) | 1.39 (1.21–1.60) | 1.15 (1.09–1.20) | 1.34 (1.19–1.52) |
| PC 1995–2013, % | 53.57 | 88.42 | ||
| APC 1995–2013, % | 2.16* | 2.56* | ||
| Age (years) | ||||
| < 50 | 0.11 (0.10–0.13) | 1.00 (Reference) | 0.11 (0.10–0.13) | 1.00 (Reference) |
| 50–59 | 0.89 (0.81–0.98) | 7.88 (6.60–9.40) | 1.03 (0.97–1.10) | 8.49 (7.25–9.95) |
| 60–69 | 2.42 (2.25–2.60) | 20.29 (17.17–23.97) | 2.48 (2.35–2.61) | 21.23 (18.23–24.73) |
| 70–79 | 3.65 (3.38–3.93) | 32.27 (27.30–38.15) | 3.99 (3.79–4.20) | 36.46 (31.31–42.46) |
| ≥ 80 | 3.38 (3.04–3.74) | 32.04 (26.69–38.47) | 4.15 (3.90–4.42) | 42.01 (35.75–49.36) |
| Gender | ||||
| Female | 0.48 (0.45–0.52) | 1.00 (Reference) | 0.57 (0.54–0.59) | 1.00 (Reference) |
| Male | 1.46 (1.39–1.53) | 3.00 (2.72–3.30) | 1.58 (1.52–1.63) | 2.65 (2.43–2.89) |
| Race | ||||
| Non-Hispanic Black | 0.42 (0.34–0.51) | 1.00 (Reference) | 0.49 (0.43–0.57) | 1.00 (Reference) |
| Non-Hispanic White | 1.08 (1.03–1.13) | 2.47 (2.03–3.01) | 1.18 (1.15–1.22) | 2.24 (1.92–2.61) |
| Hispanic | 0.65 (0.58–0.72) | 1.42 (1.15–1.77) | 0.79 (0.72–0.87) | 1.42 (1.18–1.69) |
| Other | 0.51 (0.35–0.71) | 1.17 (0.81–1.68) | 0.56 (0.50–0.62) | 1.07 (0.89–1.28) |
| Tumor stage | ||||
| Localized | 0.11 (0.10–0.13) | 1.00 (Reference) | 0.11 (0.10–0.12) | 1.00 (Reference) |
| Regional | 0.07 (0.06–0.08) | 0.60 (0.50–0.72) | 0.08 (0.08–0.09) | 0.76 (0.66–0.89) |
| Advanced | 0.56 (0.53–0.59) | 4.91 (4.30–5.59) | 0.76 (0.73–0.78) | 6.88 (6.11–7.73) |
| Unknown | 0.17 (0.16–0.19) | 1.53 (1.31–1.78) | 0.06 (0.05–0.07) | 0.55 (0.47–0.65) |
95% CI indicates 95% confidence interval.
aIncidence rate was per 100,000 persons per year and were age-adjusted to the U.S. 2000 Census using the SEER*Stat statistical program.
bRelative risk was adjusted for year of diagnosis, age, gender, and tumor stage.
*Significantly different from 0, P < 0.05.
Abbreviations. PC, percent change. APC, annual percent change.