Table 1. Association between SLC7A11-AS1 expression and clinicopathological factors of human gastric cancer.
| Characteristics | NO. of each group | SLC7A11-AS1 expression | P value | |
|---|---|---|---|---|
| Low | High | |||
| All case | 100 | 64 | 36 | |
| Age, (years, Mean ± SD) | 100 | 61.67 ± 10.28 | 63.28 ± 8.9 | 0.434 |
| Gender | 0.656 | |||
| Male | 81 | 51 | 30 | |
| Female | 19 | 13 | 6 | |
| Smoking | 0.334 | |||
| Yes | 28 | 20 | 8 | |
| No | 72 | 44 | 28 | |
| Drinking alcohol | ||||
| Yes | 26 | 14 | 12 | 0.210 |
| No | 74 | 50 | 24 | |
| BMI ( kg/m2, mean ± SD) | 100 | 21.88 ± 3.18 | 21.73 ± 2.81 | 0.809 |
| WBC (10^9/L, Mean ± SD) | 100 | 6.29 ± 2.10 | 6.44 ± 3.23 | 0.782 |
| RBC (10^12/L, Mean ± SD) | 100 | 6.58 ± 19.03 | 3.77 ± 0.80 | 0.380 |
| LY (10^9/L, Mean ± SD) | 100 | 1.44 ± 0.51 | 1.36 ± 0.56 | 0.468 |
| Hemoglobin (g/L, Mean ± SD) | 100 | 115.47 ± 29.61 | 110.28 ± 26.17 | 0.383 |
| CEA (μg/L, Mean ± SD) | 100 | 8.39 ± 12.27 | 2.86 ± 2.86 | 0.015 |
| CA19-9 (U/L, Mean ± SD) | 100 | 74.41 ± 252.63 | 17.97 ± 38.44 | 0.084 |
| TP (g/L, Mean ± SD) | 100 | 66.48 ± 11.71 | 64.99 ± 7.36 | 0.491 |
| ALB (g/L, Mean ± SD) | 100 | 39.83 ± 5.16 | 38.91 ± 5.47 | 0.404 |
| Maximum tumor diameter (cm, Mean ± SD) | 100 | 3.97 ± 1.71 | 4.60 ± 3.02 | 0.256 |
| AST (U/L, Mean ± SD) | 100 | 26.82 ± 10.68 | 27.95 ± 7.35 | 0.576 |
| ALT (IU/L, Mean ± SD) | 100 | 17.63 ± 11.46 | 18.58 ± 9.52 | 0.675 |
| TCH (mmol/L, Mean ± SD) | 100 | 4.27 ± 1.19 | 3.99 ± 1.17 | 0.257 |
| TG (mmol/L, Mean ± SD) | 100 | 1.17 ± 0.76 | 1.15 ± 0.70 | 0.902 |
| Ki-67 | 59 | 55.35% ± 16.99% | 44.38% ± 12.09 | 0.009 |
| ASA Grade | 0.593 | |||
| I | 1 | 1 | 0 | |
| II | 86 | 53 | 33 | |
| III | 14 | 10 | 3 | |
| Macroscopic types | 0.024 | |||
| Mass | 6 | 1 | 5 | |
| Ulcerative | 16 | 8 | 8 | |
| Infiltrative ulcerative | 73 | 52 | 21 | |
| Diffuse infiltrative | 5 | 3 | 2 | |
| Histology | ||||
| Undifferentiated | 10 | 8 | 2 | 0.627 |
| Poor differentiated | 54 | 35 | 19 | |
| Middle differentiated | 23 | 14 | 9 | |
| Well differentiated | 13 | 7 | 6 | |
| Depth of invasion | 0.698 | |||
| pT1 | 7 | 4 | 3 | |
| pT2 | 12 | 8 | 4 | |
| pT3 | 3 | 1 | 2 | |
| pT4 | 78 | 51 | 27 | |
| Lymph node metastasis | 0.118 | |||
| pN0 | 32 | 19 | 13 | |
| pN1 | 19 | 16 | 3 | |
| pN2 | 24 | 12 | 12 | |
| pN3 | 25 | 17 | 8 | |
| Distant metastasis | 0.007 | |||
| pM0 | 89 | 53 | 36 | |
| pM1 | 11 | 11 | 0 | |
| Tumor TNM stage | 0.024 | |||
| I | 8 | 4 | 4 | |
| II | 26 | 14 | 12 | |
| III | 55 | 35 | 20 | |
| IV | 11 | 11 | 0 | |
| Venous/Lymphatic invasion | 0.482 | |||
| Positive | 9 | 7 | 2 | |
| Negative | 91 | 57 | 34 | |
| Nervous invasion | 0.651 | |||
| Positive | 5 | 4 | 1 | |
| Negative | 95 | 60 | 35 | |
| Peritoneal metastasis | 1.000 | |||
| Absent | 99 | 63 | 36 | |
| Present | 1 | 1 | 0 | |
| Liver metastasis | 0.479 | |||
| Absent | 97 | 61 | 36 | |
| Present | 3 | 3 | 0 | |
| Ascitic fluid | 0.123 | |||
| Negative | 81 | 51 | 30 | |
| Rare | 15 | 12 | 3 | |
| Medium | 4 | 1 | 3 | |
| Fatty nodules | 0.927 | |||
| Positive | 8 | 5 | 3 | |
| Negative | 92 | 59 | 33 | |
Abbreviations: BMI, Body Mass Index; WBC, White Blood Cell; RBC, Red Blood Cell; LY, Lymphocyte Count; TP, Total Protein; ALB, Serum Albumin; AST, Aspartate Aminotransferase; ALT, Alamine Aminotransferase; TCH, Total Cholesterol; TG, Triglyceride; ASA, American Society of Anesthesiology.