Table 5. Sensitivity, specificity, positive- and negative predictive value of PD-L1 expression for diagnosis of malignancy and N-status.

		+	-	sensitivity	specificity	positive predictive value	negative predictive value
	PD-L1_4 tissue
Diagnose	controls	6	29
(tissue)	patients	35	8	81.4%	82.9%	0.854	0.784
	PD-L1_2 tissue
	controls	8	23
	patients	32	11	74.4%	74.2%	0.8	0.68
	PD-L1_4 blood
N-status	N0	11	13
(blood)	N+	17	1	94.4 %	54.2 %	0.607	0.929
	PD-L1_2 blood
	N0	8	16
	N+	15	3	83.3%	66.7%	0.652	0.842

The table shows sensitivity, specificity, positive- and negative predictive value of PD-L1 expression in tissue specimens for diagnosis of malignancy. (controls vs. patients) and of PD-L1 expression in blood samples for diagnosis of a positive N-status (N0 vs. N+).