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. 2017 Nov 8;8(68):112584–112597. doi: 10.18632/oncotarget.22576

Table 5. Sensitivity, specificity, positive- and negative predictive value of PD-L1 expression for diagnosis of malignancy and N-status.

+ - sensitivity specificity positive predictive value negative predictive value
PD-L1_4 tissue
Diagnose controls 6 29
(tissue) patients 35 8 81.4% 82.9% 0.854 0.784
PD-L1_2 tissue
controls 8 23
patients 32 11 74.4% 74.2% 0.8 0.68
PD-L1_4 blood
N-status N0 11 13
(blood) N+ 17 1 94.4 % 54.2 % 0.607 0.929
PD-L1_2 blood
N0 8 16
N+ 15 3 83.3% 66.7% 0.652 0.842

The table shows sensitivity, specificity, positive- and negative predictive value of PD-L1 expression in tissue specimens for diagnosis of malignancy. (controls vs. patients) and of PD-L1 expression in blood samples for diagnosis of a positive N-status (N0 vs. N+).