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. 2017 Nov 22;8(68):112598–112609. doi: 10.18632/oncotarget.22607

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Copyright: © 2017 Kim et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Cutoffs for maximal prediction of high/low level RFSs were determined (Table 3). The Figure shows the associations between RFS or overall survival (OS) with the levels of the six metabolites, 2PY (A), FPA (B), L-glutamine (C), uric acid (D), LPC 16:0 (E) and LPC 18:0 (F). 2PY and LPC 16:0 showed significantly better RFS at low level than high level (p = 0.037 and p = 0.035, respectively). In addition, high-level L-glutamine was associated with a better OS (p = 0.0121).

Cutoffs for maximal prediction of high/low level RFSs were determined (Table 3). The Figure shows the associations between RFS or overall survival (OS) with the levels of the six metabolites, 2PY (A), FPA (B), L-glutamine (C), uric acid (D), LPC 16:0 (E) and LPC 18:0 (F). 2PY and LPC 16:0 showed significantly better RFS at low level than high level (p = 0.037 and p = 0.035, respectively). In addition, high-level L-glutamine was associated with a better OS (p = 0.0121).