Figure 6. Suppressed expression of the imprinted gene clusters in DLK1-MEG3 region.
The chordoma samples were subjected to miRNA microarray analysis. (A, B) Expression of the two major miRNA clusters in DLK1-MEG3 region in chordoma. (C) Percentage of the up-(red) and down-(green) regulated miRNAs in the DLK-MEG3 region in chordoma. (D) KEGG analysis of the genes that correlate with MEG3 and MEG8 were enriched in different signaling pathways.