Table 1. Clinicopathological characteristics according to FBXW7 expression in 122 pancreatic cancer samples.
| Factors | FBXW7 expression | p-value | |
|---|---|---|---|
| High (n = 68) | Low (n = 54) | ||
| Age, median (range) | 69 (36–87) | 69 (36–82) | 0.299 |
| Sex | 0.166 | ||
| Male | 33 | 33 | |
| Female | 35 | 21 | |
| Histological type | 0.521 | ||
| Well | 10 | 6 | |
| Moderately, Poorly | 49 | 42 | |
| T factor (UICC) | 0.343 | ||
| T1, 2 | 7 | 3 | |
| T3, 4 | 61 | 51 | |
| Tumor size | 0.907 | ||
| ≤ 40 mm | 51 | 40 | |
| > 40 mm | 17 | 14 | |
| Lymph node metastasis | 0.432 | ||
| Absent | 18 | 11 | |
| Present | 50 | 43 | |
| Venous invasion | 0.037* | ||
| v0, 1 | 35 | 18 | |
| v2, 3 | 32 | 36 | |
| Lymphatic invasion | 0.081 | ||
| ly0, 1 | 38 | 22 | |
| ly2, 3 | 29 | 32 | |
| Perineural invasion | 0.377 | ||
| ne0, 1 | 21 | 13 | |
| ne2, 3 | 46 | 41 | |
| TNM stage (UICC) | 0.546 | ||
| I, IIA | 17 | 11 | |
| IIB, III, IV | 51 | 43 | |
| Reccurence | 0.510 | ||
| Absent | 20 | 13 | |
| Present | 48 | 41 | |
| MCL1 expression | 0.032* | ||
| Low | 47 | 27 | |
| High | 21 | 27 | |
| Ki-67 index, median (range) | 38 (0-134) | 62 (3-344) | 0.026* |
Abbreviations: UICC, Union for International Cancer Center.
*p < 0.05.