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. 2017 Dec 6;8(68):113090–113104. doi: 10.18632/oncotarget.23028

Figure 5. Comparison of drug metabolic effects in in vivo glioma models.

Figure 5

(A) Metabolic profiling comparison between in vivo U251 and T98G samples treated with TMZ by t-test statistical analysis. (B) Metabolic profiling comparison of in vivo U251 and T98G samples treated with TMZ plus MET by t-test statistical analysis. T-test statistical analysis was performed using MPP software. The dendrogram was produced by applying a hierarchical clustering algorithm. The legends color range was automatically generated by MPP, considering the minimum and maximum values of most compounds identified to highlight the best differences between samples through the most suitable color scale.