Table 1. Bax and Bad to Bcl-2 ratios in U251 and T98G cell line.
Cell line | Treatment | Bax/Bcl-2 | Bad/Bcl-2 | P value (vs control) |
---|---|---|---|---|
U251 | TMZ | 16.09 ± 2.5 | 11.8 ± 3.6 | 0.05 |
MET | 28.8 ± 3.6 | 26.4 ± 2.6 | 0.05 | |
TMZ + MET | 58.6 ± 2.5 | 35.6 ± 2.5 | 0.001 | |
T98G | TMZ | 9 ± 1.5 | 10.0 ± 2.2 | 0.05 |
MET | 9 ± 2.2 | 8.0 ± 1.8 | 0.05 | |
TMZ+MET | 18 ± 3.0 | 20.0 ± 2.6 | 0.05 |
TMZ + MET vs single treatments p < 0.001
Data are expressed as mean ± SD.