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. 2018 Jan 10;8:365. doi: 10.1038/s41598-017-18770-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The vitamin D deficient rat model was constructed successfully and the effects of maternal vitamin D deficiency on weight, blood lipid indexes and blood glucose levels for offspring. (a,b) The 25(OH)D concentrations of the VDD and CLT dams and their offspring. (c) The weight of the VDD and CLT offspring. (d) The plasma concentrations of TC, TG, HDL, and LDL of VDD and CTL offspring. (e) Blood glucose levels after the glucose injection (at 0, 15, 30, 60, 120 min) of VDD and CTL offspring at six and fourteen week of age. VDD, vitamin D deficient group; CTL, control; TC, total cholesterol; TG, triglycerides; HDL, high density lipoprotein; LDL, low density lipoprotein; Data are represented as mean ± SE; *P < 0.05.