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. 2018 Jan 10;8:363. doi: 10.1038/s41598-017-18351-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in mitochondrial network complexity. (a) Scaling of N _g/N with the area used to sample the image. (b) Changes in fractal dimension upon paraquat treatment and mitofusin 1 over-expression. (c) Z-scores expressing the deviation of the observed structure from the random configuration in Kolmogorov complexity units. Inset shows the deviation of pqt and mfn network configurations from the ctl configuration in Kolmogorov complexity units. (d) Entropy of cluster mass distributions. Perturbations of the fission/fusion balance caused a shift in the critical threshold value th* (arrows).