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. 2018 Jan 10;8:271. doi: 10.1038/s41598-017-18527-z

Figure 3.

Figure 3

TKI that reduced YAP levels caused cytotoxicity in the resistant lines. Cell viability assays performed in three resistant lines: (A) HCC827GR (B) HCC827AR or (C) HCC827GR cells in the presence of gefitinib afatinib or dasatinib. Immunoblotting demonstrated YAP protein levels (B, C,F,G,J and K) or activity (D,H and L) in the presence of different TKIs in resistant lines. The original blots were shown in Supplementary Figure S6.