Table 3.
MMR genes | Pathological grades | Cases | HR | 95% CI | P value |
---|---|---|---|---|---|
MSH2 | I | 30 | 1.24 | 0.37–4.11 | 0.72 |
II | 285 | 1.06 | 0.77–1.47 | 0.71 | |
III | 816 | 0.99 | 0.82–1.2 | 0.95 | |
MSH3 | I | 30 | 4.22 | 1.1–16.12 | 0.023* |
II | 285 | 1.15 | 0.83–1.59 | 0.4 | |
III | 816 | 1.07 | 0.88–1.29 | 0.49 | |
MSH6 | I | 30 | 4.76 | 1.24–18.19 | 0.013* |
II | 285 | 0.7 | 0.5–1 | 0.046* | |
III | 816 | 0.74 | 0.61–0.9 | 0.0021* | |
MLH1 | I | 30 | 0.48 | 0.12–1.82 | 0.27 |
II | 285 | 0.68 | 0.46–1.01 | 0.055 | |
III | 816 | 0.73 | 0.58–0.91 | 0.0056* | |
MLH3 | I | 30 | 0.9 | 0.27–2.96 | 0.86 |
II | 285 | 1.08 | 0.78–1.49 | 0.66 | |
III | 816 | 0.93 | 0.77–1.12 | 0.42 | |
PMS1 | I | 30 | 1.05 | 0.32–3.44 | 0.94 |
II | 285 | 0.92 | 0.66–1.27 | 0.6 | |
III | 816 | 0.96 | 0.79–1.16 | 0.64 | |
PMS2 | I | 30 | 0.41 | 0.09–1.92 | 0.24 |
II | 285 | 0.63 | 0.45–0.88 | 0.0071* | |
III | 816 | 0.84 | 0.67–1.04 | 0.1 |
*P < 0.05