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. 2018 Jan 10;8:406. doi: 10.1038/s41598-017-18709-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Adjusted relative risks of adiponectin levels with risk of type 2 diabetes in the updated meta-analysis. The summary estimates were obtained from the most fully-adjusted models of each study using a random-effects model. The data markers indicate the adjusted relative risks (RRs) comparing extreme tertiles of adiponectin levels. The size of the data markers indicates the weight of the study, which is the inverse variance of the effect estimate. The diamond data markers indicate the pooled RRs.