Table 3.
Follow-up characteristics of the patients with nephrin loss and the patients without nephrin loss
| Characterstics | Loss | No loss | P value |
|---|---|---|---|
| Remission, n (%) | 0.002a | ||
| Complete | 8 (61) | 27 (96) | |
| Partial | 0 (0.0) | 1 (4.0) | |
| No remission | 5 (39) | 0 (0.0) | |
| Proteinuria 16-week follow-up, g/24 h, median (IQR)c | 1.0 (0.19−2.4) | 0.15 (0.0−0.21) | 0.02b |
| eGFR 16-week follow-up, ml/min per 1.73 m2, median (IQR)d | 84 (64−110) | 88 (70−114) | 0.69b |
| Relapse, n (%) | 5 (56) | 22 (76) | 0.40a |
| Steroid resistance, n (%) | 4 (29) | 1 (3.4) | 0.03a |
| Steroid dependence, n (%) | 9 (64) | 14 (48) | 0.32a |
| Transplantation, n (%) | 1 (7.1) | 0 (0.0) | 0.34a |
| 5-Year eGFR, ml/min per 1.73 m2, median (IQR)e | 54 (42−97) | 97 (78−119) | 0.08b |
| Nonhypertensive at 5 years (%)f | 31 | 62 | 0.09g |
| FSGS at follow-up, n (%) | 3 (20) | 2 (7.4) | 0.33a |
eGFR, estimated glomerular filtration rate; FSGS, focal segmental glomerulosclerosis; IQR, interquartile range.
a
χ2 Test.
b
Mann–Whitney U test.
c
Respectively, n = 7 and n = 15.
d
Respectively, n = 11 and n = 17.
e
Respectively, n = 5 and n = 13.
f
Cumulative percentage free of events at 5-year time point.
g
z Test for difference between 2 proportions.