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Change from baseline in (a) daily urinary phosphate excretion; and (b) daily fecal phosphorous excretion in study 1 (multiple ascending dose; study drug dosed 3 times daily for 7 days) in healthy subjects with 3 dose levels of ASP3325 and placebo. No apparent time- or dose-dependent changes in these pharmacodynamic assessments were observed. Data are expressed as mean ± SD.
