Figure 3.

Three-Dimensional Models of the SCH9 Capsid

Block boundaries are represented on a schematic of the cap gene. Each parent serotype is represented by a different color (AAV9: red, AAV8: yellow, AAV2: purple) and mapped onto the AAV9 crystal structure (PDB: 3UX1) in PyMOL. (A and B) The full biological assembly (A) and a single asymmetric subunit (B) with shapes indicating the axes of symmetry are shown. Residues involved in heparin or galactose binding are annotated in green and blue, respectively, on the individual subunit.