eTable 2. The most commonly used classes of antibiotics for treatment and prophylaxis (comparison 2016 versus 2011).
2016 | 2011 | |||||||||
Class of antibiotics |
Total number of antibiotic treatments (%)* |
Prophylaxis non- surgical indication (%) |
Prophylaxis perioperative (%) |
Treatment of CI (%) |
Treatment of NI (%) |
Total number of antibiotic treatments (%)* |
Prophylaxis non-surgical indication (%) |
Prophylaxis perioperative (%) |
Treatment of CI (%) |
Treatment of NI (%) |
PeniciBLI | 5119 (23.2) | 167 (3.3) | 390 (7,6) | 3 304 (64.5) | 989 (19.3) | 1773 (12.6) | 128 (7.2) | 274 (15.5) | 866 (48.8) | 438 (24.7) |
Cephalo2 | 2856 (12.9) | 91 (3.2) | 1366 (47,8) | 1048 (36.7) | 233 (8.2) | 2054 (14.6) | 115 (5.6) | 953 (46.4) | 686 (33.4) | 234 (11.4) |
Fluoro‧chinolones | 2494 (11.3) | 188 (7.5) | 224 (9,0) | 1355 (54.3) | 591 (23.7) | 1971 (14.0) | 233 (11.8) | 231 (11.7) | 899 (45.6) | 513 (26.0) |
Cephalo3 | 1971 (8.9) | 128 (6.5) | 168 (8,5) | 1290 (65.4) | 252 (12.8) | 1498 (10.6) | 99 (6.6) | 177 (11.8) | 838 (55.9) | 313 (20.9) |
Carbapenems | 1369 (6.2) | 57 (4.2) | 41 (3,0) | 686 (50.1) | 509 (37.2) | 825 (5.9) | 46 (5.6) | 32 (3.9) | 377 (45.7) | 350 (42.4) |
Imidazole derivates |
1138 (5.2) | 40 (3.5) | 268 (23,6) | 622 (54.7) | 150 (13.2) | 741 (5.3) | 46 (6.2) | 210 (28.3) | 335 (45.2) | 118 (15.9) |
Macrolides | 833 (3.8) | 39 (4.7) | 10 (1.2) | 622 (74.7) | 71 (8.5) | 545 (3.9) | 29 (5.3) | 15 (2.8) | 356 (65.3) | 89 (16.3) |
Lincosamides | 699 (3.2) | 29 (4.1) | 103 (14.7) | 414 (59.2) | 116 (16.6) | 477 (3.4) | 23 (4.8) | 96 (20.1) | 239 (50.1) | 104 (21.8) |
PeniciES | 682 (3.1) | 83 (12.2) | 60 (8.8) | 427 (62.6) | 67 (9.8) | 765 (5.4) | 89 (11.6) | 115 (15.0) | 368 (48.1) | 142 (18.6) |
GlykopAB | 653 (3.0) | 23 (3.5) | 31 (4.7) | 277 (42.4) | 286 (43.8) | 410 (2.9) | 24 (5.9) | 18 (4.4) | 132 (32.2) | 228 (55.6) |
Other | 4 272 (19.3) | 667 (15.6) | 617 (14.4) | 1658 (38.8) | 1147 (26.8) | 3017 (21.4) | 523 (17.3) | 535 (17.7) | 1047 (34.7) | 809 (26.8) |
All absolute values refer to the number of antibiotic treatments. CI, community-acquired infection; NI, nosocomial infections; PeniBLI, combinations of penicillins with β-lactamase inhibitors; Cephalo2, second-generation cephalosporins; Cephalo3, third-generation cephalosporins; PeniciES, penicillins with extended spectrum; GlykopAB, glycopeptide antibiotics
* Referring to the total number of the mentioned classes of antibiotics of the calendar year; all other percentage values refer to the respective class of antibiotics.