Figure 6.

Functional MRI Analysis

(A) Activity in the primary visual cortex as a function of the intensity of light intensity of stimulation. T score is based on the stimulation conditions (C1, lowest luminance; C6, highest luminance), as illustrated in the boxplot. (B) Primary visual cortex activity in individual patients. The mean T score per patient is shown. Blue, treated eye before treatment; red, treated eye after treatment; yellow, untreated eye before treatment; green, untreated eye after treatment. (C) Increase in activity after treatment. Statistical parametric map showing the voxels with a significant activation (p < 0.001 uncorrected, cluster correction at p < 0.05, random effect; n = 8) after versus before treatment, all stimulation conditions together, projected onto a mean MRI template. Color bar indicates t scores.