Table 2.
n | Treatment | Control | Obestatin 1 nmol/L | Obestatin 10 nmol/L | Obestatin 100 nmol/L | UK14304 1 μmol/L | |
Lipolysis, µmol glycerol/ 100 mg lipid/90 min | 3 | Isoprenaline | 0.64 ± 0.10 | 0.61 ± 0.09 | 0.62 ± 0.10 | 0.62 ± 0.10 | 0.29 ± 0.04a |
Glucose transport, nmol 2-DG/100 mg lipids/10 min | 10 | Insulin | 0.46 ± 0.14 | 0.45 ± 0.09 | 0.45 ± 0.09 | 0.43 ± 0.09 | ND |
Fat cells were incubated with a submaximal dose of the reference activator of lipolysis (isoprenaline 100 nmol/L), or glucose transport (insulin 5 nmol/L) alone (control) or with the indicated agents. Mean ± SEM. Different from corresponding control at:
P < 0.05. ND: Not determined.