Figure 5.

Quantitative μCT and DXA Data

(A) Bone volume and total volume of intact femora and defect sites healed with BMP-2 or genetically modified muscle discs were determined from μCT data (n = 11 animals). (B) Polar moment of inertia of intact femora and defect sites bridged with BMP-2 or genetically modified muscle discs calculated from μCT data (n = 11 animals). *p < 0.05 compared to the intact femur group; †p < 0.05 compared to the genetically modified muscle group. (C) Bone mineral content (g) of intact femora and defect sites bridged or partially bridged using genetically modified muscle discs (n = 11). *p < 0.05 compared to the intact femur group; #p < 0.05 compared to the partial bridging group. Representative results are shown as box and whisker plots, with median as the horizontal bar, interquartile range calculated using Tukey hinges as the box, and the lowest and highest values represented as whiskers.