Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 12;8:1759. doi: 10.3389/fimmu.2017.01759

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Her Majesty the Queen in Right of Canada.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Properties of all antigen-specific single-domain antibodies (sdAbs) isolated from the VL383_SS, VH428 and VHB82_SS synthetic human V_H/V_L sdAb libraries. (A) Expression yields (as measured by spectrophotometry at 280 nm), T_ms (as determined by circular dichroism), and aggregation tendencies (as determined by size exclusion chromatography) of antigen-specific V_H/V_L sdAbs isolated from the libraries in comparison to the parental scaffold from which they were derived (shown in red). (B) Interoperator reproducibility in isolating individual V_H/V_L sdAb sequences.