Figure 1.

The disease risk contribution of each severe or profound condition on Counsyl Family Prep Screen is shown for a US census–weighted population. 78 conditions contributing fewer than 2 affected fetuses per 100,000 are lumped into one category (“78 Other”) for visual clarity; individual component diseases are outlined but not labeled. For each condition, the number of affected fetuses (per 100,000) is shown, along with the percentage of the total disease risk. The area of each box is proportional to the disease risk. Reported numbers include panel-wide deletion predictions when applicable (see Supplementary Methods).